Can I exercise after HPV vaccine? Yes, light exercise is fine and can actually help with arm stiffness. Maybe skip heavy weights for 48 hours if your arm is sore. Most people return to full exercise within 2-3 days. By Web Admin|2025-11-05T15:12:26+00:00November 5, 2025|HPV Vaccine Side Effects|Comments Off on Can I exercise after HPV vaccine?